Production of Recombinant Denileukin Diftitox: Assessment in the Lab-scale Bioreactor
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چکیده
منابع مشابه
Denileukin diftitox as novel targeted therapy in non-Hodgkin's lymphoma.
Non-Hodgkin's lymphoma (NHL) is a complex group of hematologic malignancies. The majority are B-cell lineage, with 10%-20% arising from T-cell lineage. Detailed knowledge of the subtypes and staging of NHL is essential to plan treatment and provide effective management of treatment-related side effects. Although numerous regimens have demonstrated efficacy in the treatment of NHL, some subtypes...
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Cutaneous T-cell lymphoma/mycosis fungoides (CTCL/MF) is a rare lymphoproliferative disorder which can present as an indolent or as an aggressive process involving skin, lymph nodes, and blood. In stages IA, IB and IIA, it is usually managed with topical medications and phototherapy. If there is progression despite application of these treatments, or if the patient presents with a higher stage ...
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15 صفحه اولRole of denileukin diftitox in the treatment of persistent or recurrent cutaneous T-cell lymphoma
Denileukin diftitox (Ontak(®)) is indicated for the treatment of patients with persistent or recurrent cutaneous T-cell lymphoma (CTCL), a rare lymphoproliferative disorder of the skin. Denileukin diftitox was the first fusion protein toxin approved for the treatment of a human disease. This fusion protein toxin combines the IL2 protein with diphtheria toxin, and targets the CD25 subunit of the...
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ژورنال
عنوان ژورنال: Research in Molecular Medicine
سال: 2019
ISSN: 2322-1348,2322-133X
DOI: 10.32598/rmm.7.3.21